PRP for facial rejuvination

PLATELET-RICH PLASMA

Platelet-rich plasma (PRP), a new biotechnology, is the product of a heightened interest in cell-based therapy and tissue engineering. This therapy is defined as an autologous preparation of plasma with concentrated platelets. PRP contains various growth factors and cytokines that enhance the body’s inherent capacity to repair and regenerate. PRP has been traditionally employed in periodontal therapy, maxillofacial surgery, orthopedics, and sports medicine. More recently, it has captured attention in the field of dermatology, particularly for its role in treating acne scars, fat grafting, wound healing, hair regrowth and improving skin texture.

PRP (PLATELET RICH PLASAA) GROWTH FACTORS AND THEIR ROLE.

  • Platelet derived growth factor (PDGF) – promotes dermal mesenchyme growth which forms hair canal. A dermal mesenchyme is a tissue of loosely connected cells located in the dermis.
  • Epidermal growth factor (EGF) — enhances growth of the hair follicles (called anagenphase) by stimulating epithelial cells and fibroblast cell division (mitosis).
  • Vascular endothelial growth factor (VEGF) – enhances hair growth and hair quality.
  • Nerve growth factor (NGF) – is a strong growth factor that also reduces the rate of programmed cell death (apoptosis).
  • Fibroblast growth factor (FGF) – stimulates the proliferation and differentiation of keratinocytes and endothelial cells.
  • Insulin like growth factor (IGF) – protects cell apoptosis by regulating the expression of messengers.

PROCEDURE DETAILS:

  1. Aspiration

The practitioner aspires a small amount of blood from the patient’s body and subjects it to centrifugation. Centrifugation is a process that separates components of whole blood — red blood cells (RBCs), white blood cells (WBCs) and platelets. RBCs, which make up 45% of the whole blood, rest at the bottom; with WBCs and platelets, making up <1% of the total blood, present in the buffy central layer. The top layer – called plasma – is supernatant and up to 55% of the total blood.

  1. Collection

Once centrifuged, platelet-rich plasma (PRP) is collected by sucking out the top supernatant layer of platelet-poor plasma (PPP), the residual volume in the tube is re-suspended by gentle inversion. PRP contains about >1,000,000/μL platelets. Total amount of PRP yielded is very small, at around 5-6 ml.

  1. Injection

The PRP is then injected into specific points over the face where it improves skin texture

ADVANTAGES OF PRP

  • Safe on patients with no side effect- as prepared out of the patient’s own blood.
  • Convenient- performed in the clinic itself, no need of long stay.
  • Completely non-toxic.
  • No risk of disease transmission.
  • Easy and simple process to perform

WHO IS CANDIDATE FOR PRP THERAPY?

  • Facial areas that appear creased and sunken
  • Reducing fine lines and wrinkles
  • Tightening and toning skin
  • Mild collagen and volume loss
  • Acne scarring
  • Rosacea
  • Overall loss of healthy, youthful skin texture and tone

COMPLICATION

  • Soreness
  • Swelling
  • Bruising

PROCEDURE SUMMARY:

Duration: 15 to 30 MINUTES

Anesthesia: local

Hospital stay: daycare procedure

Back to work: from next day

Result: permanent

Choosing a Qualified plastic Surgeon PRP injection for facial rejuvenation is a simple procedure, but excellent results require a skilled approach that can only come from specialized training and experience. You need to choose a trained and licensed plastic surgeon that can perform the procedure safely and achieve the results you desire

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