PRP FOR HAIR
PRP hair growth is a natural hair restoration solution for baldness (or alopecia). A small amount of blood is extracted with a fine needle from the individual undergoing therapy. Centrifugation is then used to separate Platelet Rich Plasma (PRP) from the blood. When injected back into the scalp of the patient who suffers from androgenic alopecia hair loss, growth factors in PRP help in hair restoration.
WHAT IS PRP?
PRP (PlateletRich Plasma) is a portion of plasma fraction of autologous blood having a high concentration of thrombocytes, and can be activated by Thrombin to release multiple growth factors, including platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF), epidermal growth factor (EGF), insulin-like growth factor (IGF), and transforming growth factor beta (TGF-β). PRP is known for the capacity to stimulate cell proliferation and differentiation. The action of platelet plasma growth factors on the development of hair follicles has already been established. PRP has also been shown to increase the yield of implanted follicular units during male baldness surgery.
PRP (PLATELETRICH PLASMA) GROWTH FACTORS AND THEIR ROLE.
•Platelet derived growth factor (PDGF) – promotes dermal mesenchyme growth which forms hair canal. A dermal mesenchyme is a tissue of loosely connected cells located in the dermis.
• Epidermal growth factor (EGF) — enhances growth of the hair follicles (called anagen phase) by stimulating epithelial cells and fibroblast cell division (mitosis).
• Vascular endothelial growth factor (VEGF) – enhances hair growth and hair quality.
• Nerve growth factor (NGF) – is a strong growth factor that also reduces the rate of programmed cell death (apoptosis).
• Fibroblast growth factor (FGF) – stimulates the proliferation and differentiation of keratinocytes and endothelial cells.
• Insulin like growth factor (IGF) – protects cell apoptosis by regulating the expression of messengers.
The practitioner aspirates a small amount of blood from the patient’s body and subjects it to centrifugation. Centrifugation is a process that separates components of whole blood — red blood cells (RBCs), white blood cells (WBCs) and platelets. RBCs, which make up 45% of the whole blood, rest at the bottom; with WBCs and platelets, making up <1% of the total blood, present in the buffy central layer. The top layer – called plasma – is supernatant and up to 55% of the total
Once centrifuged, platelet-rich plasma (PRP) is collected by sucking out the top supernatant layer of platelet-poor plasma (PPP), the residual volume in the tube is re-suspended by gentle inversion. PRP contains about >1,000,000/μL platelets. Total amount of PRP yielded is very small, at around 5-6 ml.
The PRP is then injected into specific points in your scalp where it stimulates hair re-growth
ADVANTAGES OF PRP
• Safe on patients with no side effect- as prepared out of the patient’s own blood.
• Convenient- performed in the clinic itself, no need of long stay.
• Completely non-toxic.
• No risk of disease transmission.
• Easy and simple process to perform.
Duration: 30 to 45minutes
Hospital stay: daycare procedure
Back to work: from next day
Result: permanent( variable)